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DDxPro
Possible Diagnoses
Esophagitis
Esophagitis
Substernal region pain
Weight loss
Dysphagia to solid foods
Odynophagia
Episodic dysphagia
Regurgitation
Slowly progressive over years
Unchanged over years
Vomiting
Due to delayed hypersensitiv- ity reaction to food allergens
Centrally located chest pain
Dysphagia
Esophageal food impaction
Chest pain
Chest discomfort
Heartburn
Food impaction
Long standing dysphagia
After radiation therapy
Allergic conditions
Systemic lupus erythematosus
Systemic lupus erythematosus
Arthralgia
Myalgia
Fatigue
Fever
Arthritis
Arthritis in hands
Arthritis in knees
Arthritis in wrists
Intermittent arthritis
Migratory arthritis
Nonerosive arthritis
Polyarticular arthritis
Symmetrical arthritis
Tenderness in joints
Tenderness in tendons
Anorexia
Malaise
Weight loss
Photosensitivity
Malar rash
Brucellosis
Brucellosis
Lethargy
Sweating
Weight loss
Arthralgia
Chills
Fever
Acute febrile illness
Night sweats
Joint swelling
Joint tenderness
Arthlargia
Arthlargia of hips
Arthlargia of knees
Arthlargia of spine
Malaise
Joint bursitis
Intermittent back pain
Pallor
Conjuctival contact with infected brucella material
Inhalation of infected aerosols
Gastric cancer
Gastric cancer
Epigastric pain
Slight nausea
Weight loss
Asthenia
Persistent abdominal pain
Lymphadenopathy
Nausea
Anorexia
Dysphagia
Odynophagia
Persistent vomiting
Previous gastric surgery
Palpable abdominal mass
Dysphagia in esophagogastric junction
Dysphagia in proximal stomach
Achalasia
Constant pain
Insidious upper abdominal discomfort
Mild pain
Postprandial fullness
Infectious mononucleosis
Infectious mononucleosis
Adenopathy
Lymphadenopathy
Fatigue
Low grade fever
Sweats
Dysphagia
Tonsillitis
Pharyngeal inflammation
Pharyngitis
Sore throat
Malaise
Splenomegaly
Posterior cervical lymphadenopathy
Palatal petechiae
Palatal petechiae with blotchy red macules
Palatal petechiae with streaky hemorrhages
Anorexia
Symmetrical lymphadenopathy
Chills
Ebv shedders
Pancreatic cancer
Pancreatic cancer
Asthenia
Weight loss
Anorexia
Abdominal pain
Intermittent pain
Epigastric pain
Jaundice
Intermittent abdominal pain
New onset of diabetes mellitus
Nausea
Midepigastric pain
Upper abdominal pain
Radiate to back
Radiate to sides
Hepatomegaly
Vomiting
Courvoisier sign
Trousseau syndrome
Palpable periumbilical mass
Abdominal mass
Sarcoidosis
Sarcoidosis
Lung involvement
Fatigue
Asymptomatic bilateral hilar adenopathy
Lofgren syndrome
Eye lesions
Joint lesions
Skin lesions
Diffuse interstitial lung disease
Cough
Dyspnea
Dry eyes
Migratory polyarthralgia
Painful nodules on the anterior surface of the lower extremities
Palpitations
Fever
Weight loss
Chest pain
Malaise
Erythema nodosum
Heerfordt syndrome
Diabetic amyotrophy
Diabetic amyotrophy
Weight loss
Acute asymmetric focal onset of proximal leg pain
Severe onset of proximal legs pain
Weakness of brachial plexus
Weakness of upper extremity nerves
Type 2 diabetes mellitus
Lower extremity weakness
Severe thigh pain
Unilateral
Autonomic failure
Focal proximal leg weakness
Distal sensory loss
Numbness of upper extremity nerves
Proximal sensory loss
Severe onset of back pain
Severe onset of buttock pain
Severe onset of hip pain
Severe onset of thigh pain
Lower brachial plexus weakness
Middle brachial plexus weakness
Salmonella infection
Salmonella infection
Pea soup
Watery diarrhea
Weight loss
Diarrhea
Abdominal symptoms
Enteric fever
Fever
Foodborne disease
Gastroenteritis
Poultry dairy items
Raw milk
Reptile exposure
Sickle cell disease
Undercooked eggs
Fatigue
Malaise
Chills
Headaches
Decreased skin turgor
Dry mucus membranes
Graves disease
Graves disease
Tremor
Proximal muscle weakness
Hypertension
Systolic hypertension
Toxic multinodular goiter
Deep pink skin
Emotional lability
Flat affect
Impairment of eye muscle function
Indurated plaque
Inflammation of connective tissue
Inflammation of orbital fat
Inflammation of the extraocular muscles
Lid lag
Muscle weakness
Noninflamed plaque
Orange skin
Purple color skin
Stare
Weight loss
Granulomatosis with polyangiitis
Granulomatosis with polyangiitis
Pulmonary involvement
Rhinosinusitis
Glomerulonephritis
Renal disease
Exposure to silica dust
Meningeal disease
Bloody nasal discharge
Crusting
Purulent nasal discharge
Destructive sinonasal disease
Nasal septal perforation
Saddle nose deformity
Fever
Nasal crusting
Nasal ulceration
Nasal disease
Arthralgias
Arthritis
Polyarthralgia
Weakness
Addison disease
Addison disease
Fatigue
Weight loss
Hyperpigmentation
Hyperpigmentation in palmar surfaces
Hyperpigmentation increased by sunlight
Salt craving
Hyperkalemia
Hypotension
Postural hypotension
Dehydration
Abdominal discomfort
Abdominal pain
Gi disturbance
Nausea
Vomiting
Insidious onset
Increased thirst
Failure to thrive
Morning headache
Muscle weakness
Involuntary Weight Loss
Recent institution of diuretic
Observe Repeat weight at 1–2 mo
Stable weight
Usual follow-up
Documented further IWL
Complete history, mental status, examination, diet and appetite, routine cancer screening tests
Preexisting chronic illness known to cause IWL
Reevaluate and optimize therapy
Review prescription and over-the-counter medications for anorectic side effects
Eliminate or modify offending medications
History or examination findings suggestive of illnesses known to cause IWL
Focus evaluation directed by abnormal findings
No history or examination findings suggestive of cause
CBC, SMA 12 Urinalysis Thyroid-stimulating hormone level Chest x-ray Stool guaiacs
Normal findings(CBC,SMA...)
More detailed psychosocial history: Screen for depression, anxiety, eating disorders...
Probable psychosocial cause detected
Treat Appropriate(psychosocial cause)
No abnormalities detected(psychosocial cause)
Unexplained IWL
Follow at close intervals (high risk)
Abnormal findings(CBC,SMA...)
Follow-up abnormal values
No recent institution of diuretic
Complete history, mental status, examination, diet and appetite, routine cancer screening tests
Preexisting chronic illness known to cause IWL
Reevaluate and optimize therapy
Review prescription and over-the-counter medications for anorectic side effects
Eliminate or modify offending medications
History or examination findings suggestive of illnesses known to cause IWL
Focus evaluation directed by abnormal findings
No history or examination findings suggestive of cause
CBC, SMA 12 Urinalysis Thyroid-stimulating hormone level Chest x-ray Stool guaiacs
Normal findings(CBC,SMA...)
More detailed psychosocial history: Screen for depression, anxiety, eating disorders...
Probable psychosocial cause detected
Treat Appropriate(psychosocial cause)
No abnormalities detected(psychosocial cause)
Unexplained IWL
Follow at close intervals (high risk)
Abnormal findings(CBC,SMA...)
Follow-up abnormal values
Anorexia
History Physical examination, Laboratory tests
Non-medical cause
Social factors
Psychological disorders
Depression Dementia Alcoholism Drug abuse Psychosis Anxiety Bereavement
Age-related conditions
Decreased olfactory sense Hypogeusia Visual disorders Hearing disorders Dental disorders
Eating disorders
Medical disease
Medications
Sedatives & psychotropics Digoxin Laxatives Appetite suppressants...see desc...
CNS disease
Endocrine disorders
Thyroid disease, Adrenal insufficiency, Diabetes, Hyperparathyroidism, Hypercalcemia
GI disorders
Malabsorption syndromes, Peptic ulcer, Biliary disease, Hepatitis...see desc...
Diagnostic tests: Stool for blood, fat, parasites Upper GI ...see desc .....
Other medical diseases
Chronic infection Malignancy Cardiopulmonary disease Cerebrovascular disease Abdominal ischemia
Dysphagia
History, Physical examination
EGD
Abnormal EBG
Treat Specific Structural Abnormality
Normal EGD
History suggestive of transfer dysphagia
Barium Video or Cine-Esophagography
Abnormal Barium study
Treat Dysphagia
Normal Barium study
Esophageal manometry
Abnormal manometry
Achalasia
Other motility disorders
Normal manometry
Barium Esophagography
Extrinsic compression
Functional dysphagia
History Not suggestive of transfer dysphagia
Esophageal manometry
Abnormal manometry
Achalasia
Other motility disorders
Normal manometry
Barium Esophagography
Extrinsic compression
Functional dysphagia