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A 23-year-old man with asthma and seasonal allergies

23 years old | Male

Vignette:

A 23-year-old man with asthma and seasonal allergies presents to the emergency department with an acute food bolus impaction. He has had solid food dysphagia since elementary school, but had always been told to chew more carefully. He has not had any prior evaluation, and has never been to the emergency department before, but does have a sensation of food sticking with almost every meal. He minimizes symptoms by eating slowly, chewing thoroughly, and drinking a lot of water with each bite of food. He tends to avoid dry breads and steak, as these always stick. Most of the time when foods stick, if he relaxes himself they will eventually go down. However, sometimes he has to clear the foods with regurgitation. The endoscopic exam shows a food bolus impacted in the proximal esophagus, which is cleared. The esophagus is diffusely narrowed, with edema, rings, and furrows. Biopsies show 85 eosinophils per high-power microscopy field (eos/hpf) from the distal esophagus and 70 eos/hpf from the proximal esophagus. He is started on the proton-pump inhibitor (PPI) omeprazole (20 mg orally twice daily) and has a follow-up endoscopy scheduled in 8 weeks' time. He continues to have frequent dysphagia. The endoscopic findings and biopsy results are unchanged and he is diagnosed with eosinophilic esophagitis (EoE).

Summary:

asthma | seasonal allergies | acute food bolus impaction | solid food dysphagia | chew more carefully | sensation of food sticking | alleviating by eating slowly | alleviating by chewing thoroughly | regurgitation | food bolus impacted in the proximal esophagus | frequent dysphagia

Dx:

esophagitis Eosinophilic esophagitis

Ref:

https://online.epocrates.com/diseases/130422/Eosinophilic-esophagitis/Common-Vignette

Rank

Disease

Weight

1 Esophagitis 342.0
2 Achalasia 215.0
3 Gastroesophageal reflux disease 158.0
4 Asthma 134.0
5 Churg-Strauss Syndrome 117.0
6 Infectious mononucleosis 106.0
7 Panic disorder in adults 101.0
8 Pneumonia 99.0
9 Zollinger-Ellison Syndrome 99.0
10 Barrett esophagus 99.0
11 Anaphylaxis 98.0
12 Systemic lupus erythematosus 88.0
13 Acute peptic ulcer 87.0
14 Duodenal Ulcer 87.0
15 Gastric Ulcer 87.0
16 Systemic sclerosis 87.0
17 Obstructive Sleep Apnea 86.0
18 Celiac Disease 81.0
19 Lactose intolerance 77.0
20 Rumination Syndrome 76.0
21 Hiatus hernia 74.0
22 Myasthenia Gravis 72.0
23 Allergic rhinitis 71.0
24 Fibromyalgia 71.0
25 Ichthyosis 66.0
26 Systemic vasculitis 64.0
27 Allergic conjunctivitis 64.0
28 Sarcoidosis 63.0
29 Congenital Myasthenic Syndromes 63.0
30 Neonatal Myasthenia Gravis 63.0
31 Limited cutaneous systemic sclerosis 63.0
32 Zenker diverticulum 62.0
33 Multiple Sclerosis 60.0
34 Cystic Fibrosis 59.0
35 Atopic dermatitis 58.0
36 COVID19 58.0
37 Bacterial pharyngitis 57.0
38 Tetanus 57.0
39 Granulomatosis with polyangiitis 55.0
40 Laryngeal Cancer 54.0
41 Influenza 50.0
42 Acute Rhinosinusitis 50.0
43 Stable ischemic heart disease 50.0
44 Acute viral rhinosinusitis 50.0
45 Acute bacterial rhinosinusitis 50.0
46 Gastric Volvulus 49.0
47 Subdural hematoma 49.0
48 Sialadenitis 47.0
49 Peptic Ulcer 46.0
50 Hyperthyroidism 45.0
51 Graves Disease 45.0
52 Acute respiratory failure 44.0
53 Migraine headache in adults 41.0
54 Bed bugs 41.0
55 Acute otitis media 41.0
56 Oropharyngeal and esophageal candidiasis 41.0
57 Phenylketonuria 40.0
58 Nasal polyps 40.0
59 Irritable Bowel Syndrome 40.0
60 Common cold(adults) 39.0
61 Wilson disease 39.0
62 Non-small cell lung cancer 39.0
63 Gastric cancer 38.0
64 Thyroid lymphoma 38.0
65 Mitral Stenosis 37.0
66 Aortic Dissection 37.0
67 Acute viral meningitis 36.0
68 Parkinson disease 36.0
69 Anthrax 36.0
70 Hypothyroidism 34.0
71 Muscle Layer Eosinophilic gastroenteritis 33.0
72 Cystic thyroid nodule 33.0
73 Multiple endocrine neoplasia 2A 33.0
74 Amyloidosis 31.0
75 Secondary hypogonadism 30.0
76 Acute atrial fibrillation 30.0
77 Anaplastic thyroid cancer 29.0
78 COPD Exacerbation 27.0
79 Giardiasis 26.0
80 Cholera 26.0
81 Optic neuritis 26.0
82 Neuropapillitis 26.0
83 Extraintestinal Entamoeba histolytica amebiasis 26.0
84 Substernal goiter 25.0
85 Obstructive cervical goiters 25.0
86 Acute bacterial meningitis in children 25.0
87 Toxic thyroid adenoma 25.0
88 Shigellosis 24.0
89 Chronic fatigue syndrome 22.0
90 Colorectal cancer 19.0
91 Acromegaly 19.0
92 Menopause 19.0
93 Food poisoning 19.0
94 Animal bites 19.0
95 Bullous pemphigoid 19.0
96 Non-alcoholic Fatty Liver Disease 18.0
97 Cushing syndrome 18.0
98 Aortic coarctation 18.0
99 Amphetamine use disorder 18.0
100 Crohn Disease 18.0
101 Mallory-Weiss syndrome 18.0
102 Oral candidiasis 18.0
103 Aortic stenosis 17.0
104 Analgesic nephropathy 17.0
105 Annular pancreas 16.0
106 Varicose veins 15.0
107 Heparin-induced thrombocytopenia 15.0
108 Medullary thyroid cancer 15.0
109 Chronic Lymphocytic Leukemia 14.0
110 Hypogammaglobulinemia 14.0
111 Hypertriglyceridemia 14.0
112 Alzheimer disease 14.0
113 Lung Cancer 13.0
114 Chlamydia pneumoniae infection 13.0
115 subserosal eosinophilic gastroenteritis 13.0
116 Anemia of chronic disease 12.0
117 Typhoid infection 11.0
118 Hyperparathyroidism 11.0
119 Pulmonary Embolism 10.0
120 Primary ciliary dyskinesia 10.0
121 Kartagener syndrome 10.0
122 Chronic Myeloid Leukemia 10.0
123 Oropharyngeal cancer 10.0
124 Gallstones 10.0
125 Choledocholithiasis 10.0
126 Atypical pneumonia 9.0
127 Insect bites and stings 8.0
128 Acute Lymphoblastic leukemia in children 8.0
129 Ulcerative Colitis 8.0
130 Mitral Valve Prolapse 8.0
131 Hereditary hemochromatosis 8.0
132 Drowning 8.0
133 Hereditary Angioedema 7.0
134 Hypercalcemia 7.0
135 Chronic Mitral regurgitation 7.0
136 Acute Myeloid Leukemia in adults 6.0
137 Familial Mediterranean fever 6.0
138 Acute bacterial meningitis in adults 6.0
139 Acute Cholecystitis 6.0
140 Acute Bronchitis 5.0
141 Ischemic stroke 5.0
142 Hemorrhagic stroke 5.0
143 Thrombotic thrombocytopenic purpura 5.0
144 Toxic multinodular goiter 5.0
145 Alopecia areata 3.0
146 Hyperaldosteronism 3.0
147 Primary biliary cirrhosis 3.0
148 Ankylosing spondylitis 3.0
149 Brucellosis 3.0
150 Emphysematous cholecystitis 3.0
151 Inflammatory Bowel Diseases 3.0
152 Short bowel syndrome 3.0
153 Gilbert syndrome 3.0
154 Primary sclerosing cholangitis 2.0
155 Trachoma 0.0
156 Common cold(children) 0.0
157 Dermatophyte infections 0.0
158 Sickle cell disease 0.0
159 Globus Sensation 0.0
160 Croup 0.0
161 Labyrinthitis 0.0
162 Graves ophthalmopathy 0.0
163 Motion Sickness 0.0