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Liver Disease

 Syn. Disease hepatocellular , DISORDER HEPATIC , DISORDER LIVER

Signs & Symptoms

 Right upper quadrant pain
Note: due to stretching or irritation of Glisson’s capsule, which surrounds the liver and is rich in nerve endings, Severe pain is most typical of gallbladder disease, liver abscess, and severe sinusoidal obstruction syndrome
Ref: Harrison [ 2332]
Nausea #Constitutional_symptoms #severe_liver_disease
Ref: Harrison [ 2332]
Itching
Note: early in obstructive jaundice (from biliary obstruction or drug-induced cholestasis) and somewhat later in hepatocellular disease (acute hepatitis)
Ref: Harrison [ 2332]
Fatigue #Constitutional_symptoms
Note: other reason: stress, anxiety, sleep disturbance, or a concurrent illness
Ref: Harrison [ 2333]

Physical Examination

 Abdominal distention
Ref: Harrison [ 2332]
Weakness #Constitutional_symptoms
Ref: Harrison [ 2333]
Fatigue #Constitutional_symptoms
Note: other reason: stress, anxiety, sleep disturbance, or a concurrent illness
Ref: Harrison [ 2333]

Lab / Serology

 Dark urine
Note: Patients usually report darkening of the urine before they notice scleral icterus
Ref: Harrison [ 2333]
Jaundice
Note: most reliable marker of severity.
Ref: Uptodate [ Evaluation of adults with ascites] Harrison [ 2333]
Light stools
Ref: Harrison [ 2333]

Imagin Study

 Parotid enlargement #Advanced_Liver_Disease
Ref: Uptodate [ Evaluation of adults with ascites]

Complication

Risk Factors

 Acute Hepatitis
Ref: Unknown [ 0]
Alcohol
Ref: Unknown [ 0]
Hepatitis C
Ref: Unknown [ 0]

Cause

Other