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Liver Cirrhosis

 Syn. Cirrhosis

Signs & Symptoms

 Abdominal distention
Ref: Harrison [ 2332]
Increased need for sleep
Ref: Harrison [ 2333]
Neurological manifestations
Ref: Harrison [ 2333]
Lower abdominal distension
Ref: Harrison [ 2332]

Physical Examination

 Abdominal distention
Ref: Harrison [ 2332]
Lower abdominal distension
Ref: Harrison [ 2332]
Afternoon fatigue
Ref: Harrison [ 2333]

Lab / Serology

 Thrombocytopenia #HEMATOLOGIC
Note: due to hypersplenism, due to portal hypertension
Ref: Harrison [ 2411] Cecil [ 458] Cecil [ 459]
Hypersplenism
Note: due to portal hypertension
Ref: Harrison [ 2411] Cecil [ 458]
Leukopenia #HEMATOLOGIC
Note: due to hypersplenism, due to portal hypertension
Ref: Harrison [ 2411] Cecil [ 458] Cecil [ 459]

Imagin Study

 Imaging study reveal ascites #GASTROINTESTINAL
Note: due to portal hypertension
Ref: Harrison [ 2411] Harrison [ Evaluation of adults with ascites] Cecil [ 459]
Imaging study reveal relative enlargement of the left hepatic and caudate lobes
Note: due to right lobe atrophy
Ref: Cecil [ 459]
Imaging study reveal relative enlargement of the left hepatic
Ref: Cecil [ 459]

Complication

 Variceal bleeding #GASTROINTESTINAL
Note: due to portal hypertension, cause painless hematemesis, cause melena, cause hematochezia
Ref: Cecil [ 458] Cecil [ 459]
Spontaneous bacterial peritonitis
Ref: Cecil [ 458]
Hepatic encephalopathy
Ref: Cecil [ 458]

Risk Factors

 Obesity
Ref: Epocrates [ https://online.epocrates.com/diseases/27832/Cirrhosis/Risk-Factors]
Alcohol
Ref: Epocrates [ https://online.epocrates.com/diseases/27832/Cirrhosis/Risk-Factors] Unknown [ 0]
Intravenous drug use
Ref: Epocrates [ https://online.epocrates.com/diseases/27832/Cirrhosis/Risk-Factors]

Cause

 Caused by Nonalcoholic fatty liver disease
Ref: Cecil [ 458]
Caused by alcoholic liver disease
Ref: Cecil [ 458]
Caused by hepatitis C
Ref: Cecil [ 458]

Other