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Limited Cutaneous Systemic Sclerosis

 Syn. lcSSc

Signs & Symptoms

 Family history of Scleroderma
Ref: Epocrates [ https://online.epocrates.com/diseases/59332/Limited-cutaneous-systemic-sclerosis/Risk-Factors]
Silica dust exposure
Ref: Epocrates [ https://online.epocrates.com/diseases/59332/Limited-cutaneous-systemic-sclerosis/Risk-Factors]
Dysphagia
Ref: Epocrates [ https://online.epocrates.com/diseases/59332/Limited-cutaneous-systemic-sclerosis/Risk-Factors]
Ulcers on fingers
Ref: Epocrates [ https://online.epocrates.com/diseases/59332/Limited-cutaneous-systemic-sclerosis/Risk-Factors]

Physical Examination

 bright Shiny skin extend to the trunk (negative symptom)
Ref: Epocrates [ https://online.epocrates.com/diseases/59332/Limited-cutaneous-systemic-sclerosis/Risk-Factors]
bright Shiny skin extend to the thighs (negative symptom)
Ref: Epocrates [ https://online.epocrates.com/diseases/59332/Limited-cutaneous-systemic-sclerosis/Risk-Factors]
Well-demarcated telangiectasia
Ref: Epocrates [ https://online.epocrates.com/diseases/59333/Limited-cutaneous-systemic-sclerosis/History-Exam]

Lab / Serology

 Positive antinuclear antibody
Note: with a scleroderma-specific pattern
Ref: Epocrates [ https://online.epocrates.com/diseases/59332/Limited-cutaneous-systemic-sclerosis/Risk-Factors]
Elevated Serum creatinine
Ref: Epocrates [ https://online.epocrates.com/diseases/59334/Limited-cutaneous-systemic-sclerosis/Diagnostic-Tests]
Thrombocytosis
Ref: Epocrates [ https://online.epocrates.com/diseases/59334/Limited-cutaneous-systemic-sclerosis/Diagnostic-Tests]

Imagin Study

 Claw hand deformities
Note: due to fibrosis of the skin, due to due to fibrosis of the subcutaneous tissues, due to severe atrophy of the tendons
Ref: Epocrates [ https://online.epocrates.com/diseases/59332/Limited-cutaneous-systemic-sclerosis/Risk-Factors]
Right heart enlargement
Note: due to increased Pulmonary artery pressure, due to PAH, due to pulmonary arterial hypertension
Ref: Epocrates [ https://online.epocrates.com/diseases/59334/Limited-cutaneous-systemic-sclerosis/Diagnostic-Tests]
Low diffuse capacity for carbon monoxide
Note: due to increased Pulmonary artery pressure, due to pulmonary arterial hypertension, due to PAH
Ref: Epocrates [ https://online.epocrates.com/diseases/59334/Limited-cutaneous-systemic-sclerosis/Diagnostic-Tests]

Complication

 Carpal tunnel syndrome
Note: due to hand swelling, due to inflammatory arthritis
Ref: Epocrates [ https://online.epocrates.com/diseases/59332/Limited-cutaneous-systemic-sclerosis/Risk-Factors]
Increased Pulmonary artery pressure
Note: cause right heart enlargement
Ref: Epocrates [ https://online.epocrates.com/diseases/59334/Limited-cutaneous-systemic-sclerosis/Diagnostic-Tests]
Right heart enlargement
Note: due to increased Pulmonary artery pressure, due to PAH, due to pulmonary arterial hypertension
Ref: Epocrates [ https://online.epocrates.com/diseases/59334/Limited-cutaneous-systemic-sclerosis/Diagnostic-Tests]

Risk Factors

Cause

Other