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Aortic Stenosis

 Syn. AS

Signs & Symptoms

 Chronic kidney disease
Ref: Epocrates [ https://online.epocrates.com/diseases/325/Aortic-stenosis]
Congenitally bicuspid aortic valve
Ref: Epocrates [ https://online.epocrates.com/diseases/325/Aortic-stenosis]
Exertional dizziness
Note: due to Decreased cerebral perfusion
Ref: Uptodate [ Clinical manifestations and diagnosis of aortic stenosis in adults]
Rheumatic heart disease
Ref: Epocrates [ https://online.epocrates.com/diseases/325/Aortic-stenosis]

Physical Examination

 Ejection systolic murmur
Note: ≥3/6/crescendo-decrescendo pattern that peaks in midsystole/ radiates to the carotid/loudest at the right upper sternal border
Ref: Epocrates [ https://online.epocrates.com/diseases/325/Aortic-stenosis]
Crescendo-decrescendo pattern radiates to the carotid
Note: ≥3/6/crescendo-decrescendo pattern that peaks in midsystole/ radiates to the carotid/loudest at the right upper sternal border
Ref: Epocrates [ https://online.epocrates.com/diseases/325/Aortic-stenosis]
Crescendo-decrescendo pattern peaks in midsystole
Note: ≥3/6/crescendo-decrescendo pattern that peaks in midsystole/ radiates to the carotid/loudest at the right upper sternal border
Ref: Epocrates [ https://online.epocrates.com/diseases/325/Aortic-stenosis]

Lab / Serology

 Elevated lipoprotein
Ref: Epocrates [ https://online.epocrates.com/diseases/325/Aortic-stenosis]
High LDL-cholesterol levels
Ref: Epocrates [ https://online.epocrates.com/diseases/325/Aortic-stenosis]

Imagin Study

 Dynamic obstruction at the subvalvular level (negative symptom)
Note: Septal wall most prominently affected
Ref: Epocrates [ https://online.epocrates.com/diseases/325/Aortic-stenosis]
Asymmetric hypertrophy (negative symptom)
Note: Septal wall most prominently affected
Ref: Epocrates [ https://online.epocrates.com/diseases/325/Aortic-stenosis]
Elevated aortic pressure gradient
Note: Sensitivity and specificity of the test are high
Ref: Epocrates [ https://online.epocrates.com/diseases/325/Aortic-stenosis]

Complication

 Acquired von Willebrand deficiency
Ref: Epocrates [ https://online.epocrates.com/diseases/325/Aortic-stenosis]
Severe valve obstruction
Ref: Uptodate [ Clinical manifestations and diagnosis of aortic stenosis in adults]
Easy fatigability
Ref: Uptodate [ Clinical manifestations and diagnosis of aortic stenosis in adults]

Risk Factors

 Age > 60
Ref: Epocrates [ https://online.epocrates.com/diseases/325/Aortic-stenosis]

Cause

Other