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Short Bowel Syndrome

 Syn. SBS

Signs & Symptoms

 Weight loss
Note: due to reduction in absorptive capability
Ref: Epocrates [ Short bowel syndrome]
Intentional hyperphagia
Note: due to reduction in absorptive capability
Ref: Epocrates [ Short bowel syndrome]
Dry mucous membranes
Note: due to Excessive fluid loss from the bowel
Ref: Epocrates [ Short bowel syndrome]
Diarrhea
Note: due to Increased osmolarity of the intestinal contents, due to fat malabsorption, due to bile salt irritation of the colon, due to increased gastric acid production, due to decreased intestinal transit time, due to decreased gut surface area for water reabsorption
Ref: Epocrates [ Short bowel syndrome]

Physical Examination

 laxative abuse (negative symptom)
Note: Lack of appropriate food intake
Ref: Epocrates [ Short bowel syndrome]
Low skin turgor
Note: due to Excessive fluid loss from the bowel
Ref: Epocrates [ Short bowel syndrome]
Dry mucous membranes
Note: due to Excessive fluid loss from the bowel
Ref: Epocrates [ Short bowel syndrome]

Lab / Serology

 Decreased vitamin E
Ref: Epocrates [ Short bowel syndrome]
Thrombocytopenia
Note: due to Iron deficiency , due to copper deficiency , due to folate deficiency , due to B9 deficiency , due to vitamin B12 deficiency
Ref: Epocrates [ Short bowel syndrome]
Decreased vitamin D
Ref: Epocrates [ Short bowel syndrome]

Imagin Study

 crypt hyperplasia (negative symptom)
Ref: Epocrates [ Short bowel syndrome]
Mucosal inflammation (negative symptom)
Ref: Epocrates [ Short bowel syndrome]
Mucosal ulceration (negative symptom)
Ref: Epocrates [ Short bowel syndrome]

Complication

 D-lactate acidosis
Note: due to excessive oral carbohydrate intake, carbohydrates may be metabolized by colonic bacteria to D-lactate
Ref: Epocrates [ Short bowel syndrome]
Gallstones
Ref: Epocrates [ Short bowel syndrome]
Decreased serum albumin
Note: due to Absence of parenteral nutrition, malabsorption, due to liver failure
Ref: Epocrates [ Short bowel syndrome]

Risk Factors

Cause

 Jejunoileostomy
Ref: Epocrates [ Short bowel syndrome]
Colectomy
Ref: Epocrates [ Short bowel syndrome]
Subtotal small bowel resection
Ref: Epocrates [ Short bowel syndrome]

Other