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Psychogenic Polydipsia

 Syn. PPD

Signs & Symptoms

 Nicotine
Note: Smokering is associated to symptomatic hyponatremia in polydipsia, due to Nicotine stimulates antidiuretic hormone release
Ref: Epocrates [ Psychogenic polydipsia]
Smoking
Note: Smokering is associated to symptomatic hyponatremia in polydipsia, due to Nicotine stimulates antidiuretic hormone release
Ref: Epocrates [ Psychogenic polydipsia]
Thirst suppression inability (negative symptom)
Note: As a coexist factor (this condition must be rule outed for diagnosis)
Ref: Epocrates [ Psychogenic polydipsia]
Hypothalamic thirst center malfunction (negative symptom)
Note: As a coexist factor (this condition must be rule outed for diagnosis)
Ref: Epocrates [ Psychogenic polydipsia]

Physical Examination

 Low urine osmolality
Note: Patients with PPD and a comorbid SIADH may have increased urine osmolality >500
Ref: Epocrates [ Psychogenic polydipsia]
Hypothalamic thirst center malfunction (negative symptom)
Note: As a coexist factor (this condition must be rule outed for diagnosis)
Ref: Epocrates [ Psychogenic polydipsia]
positive hepatojugular reflux (negative symptom)
Ref: Epocrates [ Psychogenic polydipsia]

Lab / Serology

 Potassium deficits
Note: By Impaired urine-concentrating ability resulting in polyuria-polydipsia
Ref: Epocrates [ Psychogenic polydipsia]
Serum sodium is elevated (negative symptom)
Ref: Epocrates [ Psychogenic polydipsia]
Low plasma osmolality
Ref: Epocrates [ Psychogenic polydipsia]

Imagin Study

 Hydronephrosis
Ref: Epocrates [ Psychogenic polydipsia]

Complication

 Bladder dilation
Ref: Epocrates [ Psychogenic polydipsia]
Urinary incontinence
Ref: Epocrates [ Psychogenic polydipsia]
Enuresis
Ref: Epocrates [ Psychogenic polydipsia]

Risk Factors

Cause

 Potassium deficits
Note: By Impaired urine-concentrating ability resulting in polyuria-polydipsia
Ref: Epocrates [ Psychogenic polydipsia]
Water-seeking
Ref: Epocrates [ Psychogenic polydipsia]
Psychiatric disorders
Ref: Epocrates [ Psychogenic polydipsia]

Other