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Common Cutaneous Drug Reactions

Signs & Symptoms

Drug intolerance

Note: due to Non-immunologic mechanisms

Ref: Epocrates [ Highlights & Basics]

Phototoxic reactions

Note: due to Non-immunologic mechanisms

Ref: Epocrates [ Highlights & Basics]

Well-demarcated oval dusky black macules

#Fixed_drug_eruption

Note: 30 minutes to 8 hours after drug administration

Ref: Uptodate [ Fixed drug eruption]

Triggered by inhaled mucolytics

#Allergic_reactions

Ref: Epocrates [ Highlights & Basics]

Physical Examination

Fixed drug reactions

Note: due to Non-immunologic mechanisms

Ref: Epocrates [ Highlights & Basics]

Photoallergic reactions

Note: due to Non-immunologic mechanisms

Ref: Epocrates [ Highlights & Basics]

Involvement of internal organ

Ref: Uptodate [ Drug reaction with eosinophilia and systemic symptoms (DRESS)]

Lab / Serology

Involvement of internal organ

Ref: Uptodate [ Drug reaction with eosinophilia and systemic symptoms (DRESS)]

Note: ALT greater than twice the upper limit of normal and/or ALP greater than 1.5 times the upper limit of normal

Ref: Uptodate [ Drug reaction with eosinophilia and systemic symptoms (DRESS)]

Note: ALT greater than twice the upper limit of normal and/or ALP greater than 1.5 times the upper limit of normal

Ref: Uptodate [ Drug reaction with eosinophilia and systemic symptoms (DRESS)]

Imagin Study

Note: ALT greater than twice the upper limit of normal and/or ALP greater than 1.5 times the upper limit of normal

Ref: Uptodate [ Drug reaction with eosinophilia and systemic symptoms (DRESS)]

Complication

Hyperpigmentation

Ref: Epocrates [ Highlights & Basics]

Risk Factors

Ref: Epocrates [ Risk Factors]

Cause

Ref: Epocrates [ History & Exam]

Ref: Uptodate [ Drug reaction with eosinophilia and systemic symptoms (DRESS)]

Ref: Uptodate [ Drug reaction with eosinophilia and systemic symptoms (DRESS)]

Other