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Anemia Of Chronic Disease

 Syn. ACD

Signs & Symptoms

 Weight loss
Note: Should prompt a search for an underlying condition.
Ref: Epocrates [ Https://online.epocrates.com/diseases/9533/Anemia-of-chronic-disease/History-Exam]
Symptoms of bleeding (negative symptom)
Ref: Epocrates [ Https://online.epocrates.com/diseases/9533/Anemia-of-chronic-disease/History-Exam]
metrorrhagia (negative symptom)
Ref: Epocrates [ Https://online.epocrates.com/diseases/9533/Anemia-of-chronic-disease/History-Exam]
menorrhagia (negative symptom)
Ref: Epocrates [ Https://online.epocrates.com/diseases/9533/Anemia-of-chronic-disease/History-Exam]

Physical Examination

 Acute infection Gr. children
Note: Typically 2 to 10 years of age
Ref: Harrison [ 688]
Normocytic anemia
Note: due to cancer, due to ckd
Ref: Uptodate [ Anemia of chronic disease/inflammation] Harrison [ 688]
Blunted response to EPO #Acute_variant_of_ACD
Ref: Uptodate [ Anemia of chronic disease/inflammation] Harrison [ 688] Cecil [ 507]

Lab / Serology

 Low transferrin saturation
Ref: Uptodate [ Anemia of chronic disease/inflammation]
Low Glomerular filtration rate #ANEMIA_OF_CHRONIC_KIDNEY_DISEASE, #CKD
Note: Of less than 30 mL/min, due to chronic kidney disease , due to CKD
Ref: Cecil [ 507]
Decreased reticulocytes
Ref: Harrison [ 688]

Imagin Study

Complication

Risk Factors

Cause

 Symptoms of bleeding (negative symptom)
Ref: Epocrates [ Https://online.epocrates.com/diseases/9533/Anemia-of-chronic-disease/History-Exam]
Melena (negative symptom)
Ref: Epocrates [ Https://online.epocrates.com/diseases/9533/Anemia-of-chronic-disease/History-Exam]
hematochezia (negative symptom)
Ref: Epocrates [ Https://online.epocrates.com/diseases/9533/Anemia-of-chronic-disease/History-Exam]

Other