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Hypertriglyceridemia

Signs & Symptoms

 Dialysis
Ref: Uptodate [ Hypertriglyceridemia in adults: Approach to evaluation] Epocrates [ Hypertriglyceridemia]
Nephrotic syndrome
Ref: Uptodate [ Hypertriglyceridemia in adults: Approach to evaluation] Epocrates [ Hypertriglyceridemia]
Glomerulonephritis
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Chronic renal failure
Ref: Uptodate [ Hypertriglyceridemia in adults: Approach to evaluation] Epocrates [ Hypertriglyceridemia]

Physical Examination

 Xanthomata palmare striatum
Ref: Uptodate [ Hypertriglyceridemia in adults: Approach to evaluation]
Tuberoeruptive xanthoma
Ref: Uptodate [ Hypertriglyceridemia in adults: Approach to evaluation]
Xanthoma of the palmar creases
Ref: Uptodate [ Hypertriglyceridemia in adults: Approach to evaluation]

Lab / Serology

 Elevated serum low-density lipoprotein
Note: Small, dense cholesterol-depleted LDL particles
Ref: Uptodate [ Hypertriglyceridemia in adults: Approach to evaluation]
Elevated fasting serum TG level
Note: Fasting triglyceride levels: Optimal: <150 mg/dL Borderline: 150 to 199 mg/dL Hypertriglyceridemia: 200 to 499 mg/dL Severe hypertriglyceridemia: ≥500 mg/dL
Ref: Uptodate [ Hypertriglyceridemia in adults: Approach to evaluation] Epocrates [ Hypertriglyceridemia]
Elevated fasting plasma TG levels
Note: Fasting triglyceride levels: Optimal: <150 mg/dL Borderline: 150 to 199 mg/dL Hypertriglyceridemia: 200 to 499 mg/dL Severe hypertriglyceridemia: ≥500 mg/dL
Ref: Uptodate [ Hypertriglyceridemia in adults: Approach to evaluation] Epocrates [ Hypertriglyceridemia]

Imagin Study

Complication

 Acute pancreatitis
Note: In TG levels >500, due to Chylomicronemia syndrome
Ref: Uptodate [ Hypertriglyceridemia in adults: Approach to evaluation] Epocrates [ Hypertriglyceridemia]

Risk Factors

 Obesity
Ref: Epocrates [ Hypertriglyceridemia]
Overweight
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Cause

 Liver disease
Note: due to Triglyceride overproduction by hepatocytes
Ref: Uptodate [ Hypertriglyceridemia in adults: Approach to evaluation] Epocrates [ Hypertriglyceridemia]
Lipodystrophic syndrome
Ref: Uptodate [ Hypertriglyceridemia in adults: Approach to evaluation]
Thiazide diuretics use
Ref: Uptodate [ Hypertriglyceridemia in adults: Approach to evaluation] Epocrates [ Hypertriglyceridemia]

Other