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Central Hypothyroidism

 Syn. secondary hypothyroidism

Signs & Symptoms

 History of Cranial irradiation
Ref: Uptodate [ Central hypothyroidism]
History of infiltrating disease
Ref: Uptodate [ Central hypothyroidism]
History of previous pituitary disease
Ref: Uptodate [ Central hypothyroidism]
History of trauma
Ref: Uptodate [ Central hypothyroidism]

Physical Examination

 Bradycardia
Note: due to Decrease in thyroid hormone
Ref: Epocrates [ Https://online.epocrates.com/diseases/3633/Central-hypothyroidism]
Delayed relaxation of deep tendon reflexes #Severe
Note: In
Ref: Epocrates [ Https://online.epocrates.com/diseases/3633/Central-hypothyroidism]
Impassive facial expression #Severe
Ref: Epocrates [ Https://online.epocrates.com/diseases/3633/Central-hypothyroidism]

Lab / Serology

 Low unbound T4 level
Ref: Harrison [ 2701]
Normal TSH levels
Ref: Harrison [ 2701]
Slightly increased TSH levels
Ref: Harrison [ 2701]

Imagin Study

Complication

Risk Factors

Cause

Other