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Crohn Disease

 Syn. CD , Crohn , regional enterocolitis

Signs & Symptoms

 Diarrhea
Ref: Uptodate [ Clinical manifestations, diagnosis and prognosis of Crohn's disease in adults]
Abdominal pain #peritonitis
Ref: Uptodate [ Acute appendicitis in adults: Clinical manifestations and diagnosis]
Abdominal tenderness
Ref: Uptodate [ Clinical manifestations, diagnosis and prognosis of Crohn's disease in adults]
Perianal skin tag
Ref: Uptodate [ Clinical manifestations, diagnosis and prognosis of Crohn's disease in adults]

Physical Examination

 Abdominal tenderness
Ref: Uptodate [ Clinical manifestations, diagnosis and prognosis of Crohn's disease in adults]
Sinus tracts
Ref: Uptodate [ Clinical manifestations, diagnosis and prognosis of Crohn's disease in adults]
Perianal skin tag
Ref: Uptodate [ Clinical manifestations, diagnosis and prognosis of Crohn's disease in adults]

Lab / Serology

 ASCA+/pANCA- pattern
Ref: Uptodate [ Clinical manifestations, diagnosis and prognosis of Crohn's disease in adults] Harrison [ 2266]
Elevated white blood cell count #Extraintestinal_Manifestations #Extended
Ref: Uptodate [ Clinical manifestations, diagnosis and prognosis of Crohn's disease in adults] Harrison [ 2264] Harrison [ 2265] Cecil [ 387]
Elevated erythrocyte sedimentation rate
Ref: Uptodate [ Clinical manifestations, diagnosis and prognosis of Crohn's disease in adults] Harrison [ 2265]

Imagin Study

 Partial obstruction
Ref: Harrison [ 2268] Cecil [ 419]
Endoscopic finding Continuous disease
Ref: Harrison [ 2267]
Endoscopic finding Cobblestoning
Ref: Harrison [ 2267]

Complication

 Amyloidosis #Extraintestinal_Manifestations #Miscellaneous_Manifestations
Ref: Cecil [ 419]
Arthritis #Extraintestinal_Manifestations #Musculoskeletal_Manifestations
Ref: Uptodate [ Toxic megacolon] Cecil [ 419]
Diaphoresis
Ref: Uptodate [ Uncomplicated gallstone disease in adults]

Risk Factors

 Age between 60 and 80
Ref: Epocrates [ https://online.epocrates.com/diseases/4232/Crohn-disease/Risk-Factors]
Family Crohn disease
Ref: Epocrates [ https://online.epocrates.com/diseases/4232/Crohn-disease/Risk-Factors]
Family history of Crohn disease
Ref: Epocrates [ https://online.epocrates.com/diseases/4232/Crohn-disease/Risk-Factors]

Cause

Other