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Ulcerative Colitis

 Syn. UC , Colitis Ulcerative , Inflammatory Bowel Disease, Ulcerative Colitis Type

Signs & Symptoms

 Diarrhea #Mild #Moderate #Severe
Ref: Uptodate [ Clinical manifestations, diagnosis, and prognosis of ulcerative colitis in adults]
History of colitis
Ref: Cecil [ 373]
Chronic diarrhea
Ref: Uptodate [ Toxic megacolon] Cecil [ 387]
Family inflammatory bowel disease
Ref: Uptodate [ Clinical manifestations, diagnosis and prognosis of Crohn's disease in adults]

Physical Examination

 Chronic diarrhea
Ref: Uptodate [ Toxic megacolon] Cecil [ 387]
Abdominal tenderness #Severe #Moderate
Ref: Uptodate [ Clinical manifestations, diagnosis, and prognosis of ulcerative colitis in adults] Harrison [ 2263]
Erythema nodosum #Extraintestinal_Manifestations #Skin_Manifestations
Ref: Cecil [ 420]

Lab / Serology

 Increased levels of perinuclear antineutrophil cytoplasmic antibodies
Ref: Harrison [ 2266] Cecil [ 420]
ASCA-/pANCA+ pattern
Ref: Uptodate [ Clinical manifestations, diagnosis and prognosis of Crohn's disease in adults]
Elevated acute phase reactants
Ref: Uptodate [ Clinical manifestations, diagnosis and prognosis of Crohn's disease in adults]

Imagin Study

 Radiographic finding Small bowel significantly abnormal (negative symptom)
Ref: Harrison [ 2716]
endoscopic finding Cobblestoning (negative symptom)
Ref: Harrison [ 2267]
Endoscopic finding Continuous disease
Ref: Harrison [ 2267]

Complication

 Diaphoresis
Ref: Uptodate [ Uncomplicated gallstone disease in adults]
Elevated serum gamma glutamyl transpeptidase
Ref: Uptodate [ Clinical manifestations, diagnosis and prognosis of Crohn's disease in adults]
Elevated serum alkaline phosphatase
Ref: Uptodate [ Clinical manifestations, diagnosis and prognosis of Crohn's disease in adults]

Risk Factors

 Family history of inflammatory bowel disease
Ref: Uptodate [ Clinical manifestations, diagnosis and prognosis of Crohn's disease in adults] Epocrates [ https://online.epocrates.com/diseases/4332/Ulcerative-colitis/Risk-Factors]

Cause

Other