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Follicular Thyroid Carcinoma

Signs & Symptoms

 History of radiation exposure during childhood
Note: (Less than 18 years)
Ref: Uptodate [ Follicular thyroid cancer (including Hürthle cell cancer)] Harrison [ 2714]
History of thyroid cancer in a first degree relative
Ref: Uptodate [ Follicular thyroid cancer (including Hürthle cell cancer)] Harrison [ 2714]
Iodine-deficient regions
Ref: Uptodate [ Follicular thyroid cancer (including Hürthle cell cancer)] Harrison [ 2715]
PAX8-PPAR gamma 1 gene rearrangement
Ref: Uptodate [ Follicular thyroid cancer (including Hürthle cell cancer)] Harrison [ 2715]

Physical Examination

Lab / Serology

 Mutations
Ref: Uptodate [ Follicular thyroid cancer (including Hürthle cell cancer)] Harrison [ 2715]
Genetic rearrangement
Ref: Uptodate [ Follicular thyroid cancer (including Hürthle cell cancer)] Harrison [ 2715]
Well-differentiated epithelium with follicular development and colloid
Note: Associated with good prognosis
Ref: Uptodate [ Follicular thyroid cancer (including Hürthle cell cancer)]

Imagin Study

 Uninodular
Ref: Uptodate [ Follicular thyroid cancer (including Hürthle cell cancer)]
Functional metastases
Ref: Uptodate [ Follicular thyroid cancer (including Hürthle cell cancer)]

Complication

Risk Factors

 Female
Ref: Uptodate [ Follicular thyroid cancer (including Hürthle cell cancer)]
Age between 40 and 60
Ref: Uptodate [ Follicular thyroid cancer (including Hürthle cell cancer)]

Cause

Other