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Infectious Mononucleosis

 Syn. mononucleosis

Signs & Symptoms

 Low grade fever
Ref: Uptodate [ Infectious mononucleosis in adults and adolescents] Harrison [ 1358]
Lymphadenopathy
Note: Peaks in the first week and then gradually subsides over two to three weeks, rare in elderly patients
Ref: Uptodate [ Infectious mononucleosis in adults and adolescents] Harrison [ 1358]
Sweats
Ref: Uptodate [ Infectious mononucleosis in adults and adolescents]
Adenopathy
Note: Peaks in the first week and then gradually subsides over two to three weeks, rare in elderly patients
Ref: Uptodate [ Infectious mononucleosis in adults and adolescents] Harrison [ 1358]

Physical Examination

 Tonsillitis
Ref: Uptodate [ Infectious mononucleosis in adults and adolescents] Harrison [ 1359]
Pharyngitis
Note: rare in elderly patients
Ref: Uptodate [ Infectious mononucleosis in adults and adolescents] Harrison [ 1358]
Pharyngeal inflammation
Note: rare in elderly patients
Ref: Uptodate [ Infectious mononucleosis in adults and adolescents] Harrison [ 1358]

Lab / Serology

 Elevated aminotransferases
Ref: Uptodate [ Infectious mononucleosis in adults and adolescents]
Positive EBV-specific antibodies test
Ref: Uptodate [ Infectious mononucleosis in adults and adolescents]
Presence of VCA IgM antibodies
Ref: Uptodate [ Infectious mononucleosis in adults and adolescents]

Imagin Study

Complication

 Cerebellar ataxia
Note: due to Meningitis, due to encephalitis
Ref: Harrison [ 1359]
Low hematocrit
Note: due to Splenic rupture
Ref: Uptodate [ Infectious mononucleosis in adults and adolescents] Harrison [ 1359]
Falling hematocrit
Note: due to Splenic rupture, Typically occurs about 14 days after symptom onset
Ref: Uptodate [ Infectious mononucleosis in adults and adolescents] Harrison [ 1359]

Risk Factors

Cause

Other