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Signs & Symptoms
Rice-water diarrhea
Note: Diarrhea >1 liter/hour is almost pathognomonic of cholera if sustained (>20 mL/kg during a 4-hour observation period)
Ref:
Epocrates
[ https://online.epocrates.com/diseases/45132/Cholera/Risk-Factors]
Higher gastric pH
Ref:
Epocrates
[ https://online.epocrates.com/diseases/45132/Cholera/Risk-Factors]
Decreased gastric acid secretion
Ref:
Epocrates
[ https://online.epocrates.com/diseases/45132/Cholera/Risk-Factors]
Ingestion of contaminated water
Ref:
Epocrates
[ https://online.epocrates.com/diseases/45132/Cholera/Risk-Factors]
Physical Examination
Hypovolemia
Ref:
Uptodate
[ Cholera: Clinical features, diagnosis, treatment, and prevention]
Significant decrease blood pressure
Note: evidence of a significant (>20 mmHg) postural drop in blood pressure (BP)
Ref:
Epocrates
[ https://online.epocrates.com/diseases/45133/Cholera/History-Exam]
Mildly decreased skin turgor
Ref:
Epocrates
[ https://online.epocrates.com/diseases/45133/Cholera/History-Exam]
Lab / Serology
High potassium in stool
Ref:
Uptodate
[ Cholera: Clinical features, diagnosis, treatment, and prevention]
High sodium in stool
Ref:
Uptodate
[ Cholera: Clinical features, diagnosis, treatment, and prevention]
Retinol deficiency
Ref:
Uptodate
[ Cholera: Clinical features, diagnosis, treatment, and prevention]
Harrison
[ 1187]
Complication
Wrinkled hands
Note: due to Hypovolemia
Ref:
Uptodate
[ Cholera: Clinical features, diagnosis, treatment, and prevention]
Harrison
[ 1187]
Rapid peripheral pulse
Note: due to Hypovolemia
Ref:
Uptodate
[ Cholera: Clinical features, diagnosis, treatment, and prevention]
Harrison
[ 1187]
Low blood pressure
Note: due to Hypovolemia
Ref:
Uptodate
[ Cholera: Clinical features, diagnosis, treatment, and prevention]
Harrison
[ 1187]