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Gilbert Syndrome

 Syn. Constitutional hepatic dysfunction , Familial nonhemolytic jaundice , Gilberts syndrome

Signs & Symptoms

 Episodes of mild jaundice
Ref: Uptodate [ Gilbert syndrome and unconjugated hyperbilirubinemia due to bilirubin overproduction]
Triggered by Dehydration
Ref: Uptodate [ Gilbert syndrome and unconjugated hyperbilirubinemia due to bilirubin overproduction]
Breast cancer
Ref: Uptodate [ Gilbert syndrome and unconjugated hyperbilirubinemia due to bilirubin overproduction]
Puberty
Ref: Harrison [ 2345]

Physical Examination

 Increased plasma bilirubin concentrations
Ref: Uptodate [ Gilbert syndrome and unconjugated hyperbilirubinemia due to bilirubin overproduction]
Scleral icterus
Note: During an episode only
Ref: Uptodate [ Gilbert syndrome and unconjugated hyperbilirubinemia due to bilirubin overproduction]

Lab / Serology

 Mild jaundice
Ref: Uptodate [ Gilbert syndrome and unconjugated hyperbilirubinemia due to bilirubin overproduction]
Mild unconjugated hyperbilirubinemia
Ref: Uptodate [ Gilbert syndrome and unconjugated hyperbilirubinemia due to bilirubin overproduction] Harrison [ 2344]
Intermittent jaundice
Note: due to predominantly unconjugated hyperbilirubinemia
Ref: Uptodate [ Gilbert syndrome and unconjugated hyperbilirubinemia due to bilirubin overproduction]

Imagin Study

Complication

Risk Factors

 Adolescent
Ref: Uptodate [ Gilbert syndrome and unconjugated hyperbilirubinemia due to bilirubin overproduction]
Male
Ref: Uptodate [ Gilbert syndrome and unconjugated hyperbilirubinemia due to bilirubin overproduction]

Cause

Other