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Signs & Symptoms
Fatigue
Ref:
Uptodate
[ Diagnosis and differential diagnosis of systemic lupus erythematosus in adults Overview of the clinical manifestations of systemic lupus erythematosus in adults]
Harrison
[ 2518, 2520]
Cecil
[ 780]
Myalgia
Ref:
Uptodate
[ Diagnosis and differential diagnosis of systemic lupus erythematosus in adults Overview of the clinical manifestations of systemic lupus erythematosus in adults]
Harrison
[ 2518, 2520]
Cecil
[ 780]
Arthralgia
Ref:
Uptodate
[ Diagnosis and differential diagnosis of systemic lupus erythematosus in adults Overview of the clinical manifestations of systemic lupus erythematosus in adults]
Harrison
[ 2518, 2520]
Cecil
[ 780]
Exposure to ultraviolet light
Note: Causes flares of SLE.
Ref:
Harrison
[ 2516]
Physical Examination
Audible pericardial rub
Note: due to Pericarditis
Ref:
Uptodate
[ Non-coronary cardiac manifestations of systemic lupus erythematosus in adults]
Abnormal breath sounds
Note: due to Pleural effusion, due to Pneumonitis, due to Interstitial lung disease
Ref:
Uptodate
[ Diagnosis and differential diagnosis of systemic lupus erythematosus in adults Overview of the clinical manifestations of systemic lupus erythematosus in adults]
Decreased breath sounds
Note: due to Pleural effusion, due to Pneumonitis, due to Interstitial lung disease
Ref:
Uptodate
[ Diagnosis and differential diagnosis of systemic lupus erythematosus in adults Overview of the clinical manifestations of systemic lupus erythematosus in adults]
Lab / Serology
Antinuclear antibody
#Criteria
Note: Highly specific
Ref:
Uptodate
[ Drug-induced lupus]
Harrison
[ 2517, 2518]
Cecil
[ 782]
Anti-histone antibody
Note: More frequent in drug-induced lupus.
Ref:
Harrison
[ 2517, 2525]
Cecil
[ 783]
Anti ds-DNA antibody
#Criteria #lupus_nephritis
Note: Highly specific. Associated with lupus nephritis.
Ref:
Uptodate
[ Drug-induced lupus]
Harrison
[ 2517, 2518, 2525]
Cecil
[ 782]
Imagin Study
ST wave abnormalities
Note: due to Myocarditis
Ref:
Uptodate
[ Non-coronary cardiac manifestations of systemic lupus erythematosus in adults]
Diffuse opacities in the lower lung zones
Note: due to Acute pneumonitis, due to Pulmonary hemorrhage
Ref:
Uptodate
[ Pulmonary manifestations of systemic lupus erythematosus in adults]
Diffuse opacities
Note: due to Acute pneumonitis, due to Pulmonary hemorrhage
Ref:
Uptodate
[ Pulmonary manifestations of systemic lupus erythematosus in adults]
Complication
Infection
Ref:
Uptodate
[ Musculoskeletal manifestations of systemic lupus erythematosus]
Pleurisy
Ref:
Uptodate
[ Diagnosis and differential diagnosis of systemic lupus erythematosus in adults Overview of the clinical manifestations of systemic lupus erythematosus in adults]
Harrison
[ 2518, 2520]
Cecil
[ 780]
Pleuritis
Ref:
Uptodate
[ Diagnosis and differential diagnosis of systemic lupus erythematosus in adults Overview of the clinical manifestations of systemic lupus erythematosus in adults]
Harrison
[ 2518, 2520]
Cecil
[ 780]
Risk Factors
Female
Ref:
Uptodate
[ Diagnosis and differential diagnosis of systemic lupus erythematosus in adults Overview of the clinical manifestations of systemic lupus erythematosus in adults]
Young
Ref:
Uptodate
[ Diagnosis and differential diagnosis of systemic lupus erythematosus in adults Overview of the clinical manifestations of systemic lupus erythematosus in adults]
Smoking
Ref:
Harrison
[ 2517]