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Pheochromocytoma

 Syn. Chromaffin tumors

Signs & Symptoms

 Episodic headache
Ref: Uptodate [ Clinical presentation and diagnosis of pheochromocytoma] Harrison [ 2740] Cecil [ 651]
Sweating
Ref: Uptodate [ Clinical presentation and diagnosis of pheochromocytoma] Harrison [ 2740] Cecil [ 651]
Generalized weakness
Ref: Uptodate [ Clinical presentation and diagnosis of pheochromocytoma] Harrison [ 2740] Cecil [ 651]
Panic attack-type symptoms
Ref: Uptodate [ Clinical presentation and diagnosis of pheochromocytoma] Harrison [ 2740]

Physical Examination

 Paradoxical response to antihypertensive drugs
Ref: Harrison [ 2740] Cecil [ 651]
Pressor response during anesthesia
Ref: Uptodate [ Clinical presentation and diagnosis of pheochromocytoma] Harrison [ 2740]
Pressor response during angiography
Ref: Uptodate [ Clinical presentation and diagnosis of pheochromocytoma] Harrison [ 2740]

Lab / Serology

 Impaired fasting glucose
Note: due to Catecholamine excess
Ref: Uptodate [ Clinical presentation and diagnosis of pheochromocytoma]
Zellballen pattern
Note: Histopathology
Ref: Harrison [ 2740]
Elevated Plasma free metanephrine level
Note: Plasma free metanephrine level greater than 0.61 nmol/L
Ref: Uptodate [ Clinical presentation and diagnosis of pheochromocytoma] Harrison [ 2740] Cecil [ 651]

Imagin Study

 Intraadrenal tumor
Ref: Uptodate [ Clinical presentation and diagnosis of pheochromocytoma] Harrison [ 2739] Cecil [ 650]
Tumor in the abdomen
Ref: Uptodate [ Clinical presentation and diagnosis of pheochromocytoma]
Adrenal mass
Note: Average tumor size of 4.9 cm
Ref: Uptodate [ Clinical presentation and diagnosis of pheochromocytoma] Harrison [ 2739]

Complication

 Anxiety
Ref: Uptodate [ Clinical presentation and diagnosis of pheochromocytoma] Harrison [ 2740] Cecil [ 651]
Cardiomyopathy
Note: due to Catecholamine excess
Ref: Uptodate [ Clinical presentation and diagnosis of pheochromocytoma] Harrison [ 2740] Cecil [ 651]
Psychiatric disorders
Ref: Uptodate [ Clinical presentation and diagnosis of pheochromocytoma] Harrison [ 2740] Cecil [ 651]

Risk Factors

 Age between 30 and 50
Ref: Uptodate [ Clinical presentation and diagnosis of pheochromocytoma]

Cause

Other