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Papillary Thyroid Cancer

 Syn. Papillary thyroid carcinoma

Signs & Symptoms

 Hepatitis C
Ref: Uptodate [ Papillary thyroid cancer]
Hepatitis C-related chronic hepatitis
Ref: Uptodate [ Papillary thyroid cancer]
Familly history of thyroid cancer syndrome
Note: 10-fold increased risk
Ref: Uptodate [ Papillary thyroid cancer] Harrison [ 2714]
Family history of thyroid cancer
Note: 10-fold increased risk
Ref: Uptodate [ Papillary thyroid cancer] Harrison [ 2714]

Physical Examination

 Thyroid nodule
Note: May be palpable or nonpalpable
Ref: Uptodate [ Papillary thyroid cancer] Harrison [ 2714]

Lab / Serology

 Unencapsulated #Classic
Ref: Uptodate [ Papillary thyroid cancer]
Contain calcified psammoma bodies
Ref: Uptodate [ Papillary thyroid cancer]
Eosinophilic cytoplasm that are twice as tall as they are wide #Tall_cell
Ref: Uptodate [ Papillary thyroid cancer]

Imagin Study

 Lymph node involvement
Ref: Uptodate [ Papillary thyroid cancer] Harrison [ 2715]
Fixation of the nodule to surrounding tissues #Malignant
Ref: Uptodate [ Papillary thyroid cancer] Harrison [ 2714]
Multifocal
Ref: Uptodate [ Papillary thyroid cancer] Harrison [ 2715]

Complication

 Lymph node involvement
Ref: Uptodate [ Papillary thyroid cancer] Harrison [ 2715]
Metastases
Note: Two-thirds have pulmonary and one-fourth have skeletal metastases. Rarer sites of metastasis are the brain, kidneys, liver, and adrenals
Ref: Uptodate [ Papillary thyroid cancer] Harrison [ 2715]

Risk Factors

Cause

Other