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Henoch-Schonlein Purpura

 Syn. Henoch-Schönlein purpura , IgAV , IgA vasculitis

Signs & Symptoms

 Oligoarticular
Ref: Uptodate [ IgA vasculitis (Henoch-Schönlein purpura): Clinical manifestations and diagnosis] Harrison [ 2586] Cecil [ 795]
Limited joint range of motion
Ref: Uptodate [ IgA vasculitis (Henoch-Schönlein purpura): Clinical manifestations and diagnosis] Harrison [ 2586] Cecil [ 795]
Arthralgia
Ref: Uptodate [ IgA vasculitis (Henoch-Schönlein purpura): Clinical manifestations and diagnosis] Harrison [ 2586] Cecil [ 795]
Polyarthralgia
Ref: Uptodate [ IgA vasculitis (Henoch-Schönlein purpura): Clinical manifestations and diagnosis] Harrison [ 2586] Cecil [ 795]

Physical Examination

 Purpura over the buttocks #Criteria
Ref: Uptodate [ IgA vasculitis (Henoch-Schönlein purpura): Clinical manifestations and diagnosis] Harrison [ 2586] Cecil [ 795]
Purpura with lower limb predominance #Criteria
Ref: Uptodate [ IgA vasculitis (Henoch-Schönlein purpura): Clinical manifestations and diagnosis] Harrison [ 2586] Cecil [ 795]
Palpable purpura #Criteria
Ref: Uptodate [ IgA vasculitis (Henoch-Schönlein purpura): Clinical manifestations and diagnosis] Harrison [ 2586] Cecil [ 795]

Lab / Serology

 Elevated IgA level
Ref: Harrison [ 2586]
Granulocytes in the walls of small arterioles #Criteria
Ref: Uptodate [ IgA vasculitis (Henoch-Schönlein purpura): Clinical manifestations and diagnosis]
Granulocytes in the walls of small venules #Criteria
Ref: Uptodate [ IgA vasculitis (Henoch-Schönlein purpura): Clinical manifestations and diagnosis]

Imagin Study

Complication

Risk Factors

 Age < 20
Ref: Uptodate [ UTD:IgA vasculitis (Henoch-Schönlein purpura): Clinical manifestations and diagnosis]
Male
Ref: Uptodate [ UTD:IgA vasculitis (Henoch-Schönlein purpura): Clinical manifestations and diagnosis]

Cause

Other