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Optic Neuritis

 Syn. INFLAMMATORY OPTIC NEUROPATHY

Signs & Symptoms

 Eye pain
Ref: Uptodate [ Optic neuritis: Pathophysiology, clinical features, and diagnosis] Vaughan [ 636] BCSC [ 96]
Significant decrease in central visual acuity
Ref: Uptodate [ Optic neuritis: Pathophysiology, clinical features, and diagnosis]
Loss of color of vision
Note: out of proportion to the loss of visual acuity
Ref: Uptodate [ Optic neuritis: Pathophysiology, clinical features, and diagnosis] BCSC [ 96]
Acute vision loss
Note: Over a period of hours to days
Ref: Uptodate [ Optic neuritis: Pathophysiology, clinical features, and diagnosis] Vaughan [ 635] BCSC [ 96]

Physical Examination

 Afferent pupillary defect
Ref: Uptodate [ Optic neuritis: Pathophysiology, clinical features, and diagnosis] Vaughan [ 636] BCSC [ 96]
cotton-wool spots (negative symptom)
Ref: Vaughan [ 636] BCSC [ 97]
Temporal pallor of disc
Note: It occurs following the attack
Ref: Uptodate [ Optic neuritis: Pathophysiology, clinical features, and diagnosis]

Lab / Serology

Imagin Study

 Optic nerve inflammation
Ref: Uptodate [ Optic neuropathies] Vaughan [ 637] BCSC [ 97]
Increased signal
Ref: Uptodate [ Optic neuropathies] Vaughan [ 637] BCSC [ 97]
Gadolinium enhancement
Ref: Uptodate [ Optic neuropathies] Vaughan [ 637] BCSC [ 97]

Complication

Risk Factors

 20 < age < 40
Ref: Uptodate [ Optic neuritis: Pathophysiology, clinical features, and diagnosis]
Age between 20 and 40
Ref: Uptodate [ Optic neuritis: Pathophysiology, clinical features, and diagnosis]
Female
Ref: Uptodate [ Optic neuritis: Pathophysiology, clinical features, and diagnosis]

Cause

Other