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Testicular Cancer

 Syn. Malignant neoplasm of testis , Cancer of the Testis

Signs & Symptoms

 Testicular discomfort
Ref: Harrison [ 632]
History of cancer of the other testicle
Ref: Uptodate [ Causes of painless scrotal swelling in children and adolescents]
Family history of testicular cancer
Ref: Uptodate [ Causes of painless scrotal swelling in children and adolescents]
Cryptorchidism
Ref: Uptodate [ Causes of painless scrotal swelling in children and adolescents]

Physical Examination

 Testicular Firmness
Ref: Harrison [ 632]
Painless scrotal mass
Ref: Uptodate [ Causes of painless scrotal swelling in children and adolescents] Harrison [ 632]
Testicular enlargement
Ref: Uptodate [ Causes of painless scrotal swelling in children and adolescents]

Lab / Serology

 Elevated AFP
Ref: Uptodate [ Clinical manifestations, diagnosis, and staging of testicular germ cell tumors] Harrison [ 633]
Elevated beta-hCG
Ref: Uptodate [ Clinical manifestations, diagnosis, and staging of testicular germ cell tumors] Harrison [ 633]
Elevated lactate dehydrogenase
Ref: Uptodate [ Clinical manifestations, diagnosis, and staging of testicular germ cell tumors] Harrison [ 633]

Imagin Study

 Irregular scrotal mass
Note: Is seen in Embryonal carcinoma or teratocarcinoma
Ref: Uptodate [ Clinical manifestations, diagnosis, and staging of testicular germ cell tumors]
Irregular scrotal mass with indiscrete borders
Note: Is seen in Embryonal carcinoma or teratocarcinoma
Ref: Uptodate [ Clinical manifestations, diagnosis, and staging of testicular germ cell tumors]
Rubbery enlargement
Note: Is seen in Seminoma
Ref: Uptodate [ Clinical manifestations, diagnosis, and staging of testicular germ cell tumors]

Complication

 Hydrocele
Ref: Uptodate [ Clinical manifestations, diagnosis, and staging of testicular germ cell tumors]
Gynecomastia
Note: due to Production of human chorionic gonadotropin, due to Production of hCG
Ref: Uptodate [ Causes of painless scrotal swelling in children and adolescents]
Hyperthyroidism
Note: due to Production of human chorionic gonadotropin, due to Production of hCG
Ref: Uptodate [ Clinical manifestations, diagnosis, and staging of testicular germ cell tumors]

Risk Factors

Cause

Other