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Sarcoidosis

 Syn. Boeck Disease , lymphogranulomatosis , schaumann syndrome

Signs & Symptoms

 Fatigue
Ref: Uptodate [ Clinical manifestations and diagnosis of pulmonary sarcoidosis] Uptodate [ Extrapulmonary manifestations of sarcoidosis] Harrison [ 2601]
Recent use of oxaliplatin (negative symptom)
Note: Raise the possibility of Drug-induced hypersensitivity
Ref: Uptodate [ Clinical manifestations and diagnosis of pulmonary sarcoidosis]
Recent use of amoxicillin (negative symptom)
Note: Raise the possibility of Drug-induced hypersensitivity
Ref: Uptodate [ Clinical manifestations and diagnosis of pulmonary sarcoidosis]
Recent use of sirolimus (negative symptom)
Note: Raise the possibility of Drug-induced hypersensitivity
Ref: Uptodate [ Clinical manifestations and diagnosis of pulmonary sarcoidosis]

Physical Examination

 Seizures
Ref: Harrison [ 2603]
Keloid formation
Ref: Harrison [ 2601]
Hyperpigmentation
Ref: Harrison [ 2601]

Lab / Serology

 Elevated ACE level
Ref: Uptodate [ Clinical manifestations and diagnosis of pulmonary sarcoidosis] Harrison [ 2605]
Hyperglobulinemia
Ref: Uptodate [ Clinical manifestations and diagnosis of pulmonary sarcoidosis]
Elevated bilirubin level
Ref: Harrison [ 2603]

Imagin Study

 Hilar mediastinal adenopathy
Note: due to lymph node involvement
Ref: Uptodate [ Extrapulmonary manifestations of sarcoidosis]
Paratracheal mediastinal adenopathy
Note: due to lymph node involvement
Ref: Uptodate [ Extrapulmonary manifestations of sarcoidosis]
Lambda sign
Ref: Uptodate [ Extrapulmonary manifestations of sarcoidosis]

Complication

 Pulmonary hypertension
Note: due to Advanced lung fibrosis
Ref: Uptodate [ Clinical manifestations and diagnosis of pulmonary sarcoidosis] Harrison [ 2601]
Syncope
Note: due to Cardiovascular involvement
Ref: Uptodate [ Clinical manifestations and diagnosis of pulmonary sarcoidosis]
Venous thromboembolic disease
Ref: Uptodate [ Clinical manifestations and diagnosis of pulmonary sarcoidosis]

Risk Factors

 Age between 20 and 60
Ref: Uptodate [ Clinical manifestations and diagnosis of pulmonary sarcoidosis]
Black ethnicity
Ref: Harrison [ 2600]

Cause

Other