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Signs & Symptoms
Involve ankle joints
Ref:
Epocrates
[ https://online.epocrates.com/diseases/1332/Gout/Risk-Factors]
Lower extremity involvement
#Typical_gout_flare
Note: Knee and First metatarsophalangeal joint
Ref:
Uptodate
[ Clinical manifestations and diagnosis of gout]
Lower extremity joints swelling
#Typical_gout_flare
Ref:
Uptodate
[ Clinical manifestations and diagnosis of gout]
Involve tarsometatarsal joints
Ref:
Epocrates
[ https://online.epocrates.com/diseases/1332/Gout/Risk-Factors]
Physical Examination
Lower extremity joints warmth
#Typical_gout_flare
Ref:
Uptodate
[ Clinical manifestations and diagnosis of gout]
Lower extremity joints Redness
#Typical_gout_flare
Ref:
Uptodate
[ Clinical manifestations and diagnosis of gout]
Lower extremity joints swelling
#Typical_gout_flare
Ref:
Uptodate
[ Clinical manifestations and diagnosis of gout]
Lab / Serology
Presence of monosodium urate crystals
Note: Even during the asymptomatic intercritical period
Ref:
Uptodate
[ Clinical manifestations and diagnosis of gout]
Harrison
[ 2632]
positive birefringent urate crystals
(negative symptom)
Note: CPPD with Weakly positively birefringent crystals
Ref:
Uptodate
[ Clinical manifestations and diagnosis of gout]
Vitamin B12 deficiency
Ref:
Uptodate
[ Clinical manifestations and diagnosis of gout]
Imagin Study
Overhanging edges of bone
Note: Occur with more chronic disease
Ref:
Uptodate
[ Clinical manifestations and diagnosis of gout]
Double contour sign
Ref:
Uptodate
[ Clinical manifestations and diagnosis of gout]
Well-defined erosions with sclerotic margins soft tissue masses on X-ray
Ref:
Harrison
[ 2632]
Risk Factors
Obesity
Ref:
Uptodate
[ Clinical manifestations and diagnosis of gout]
Epocrates
[ https://online.epocrates.com/diseases/1332/Gout/Risk-Factors]
Male
Ref:
Uptodate
[ Clinical manifestations and diagnosis of gout]
Hypertension
Ref:
Uptodate
[ Clinical manifestations and diagnosis of gout]