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Autoimmune Pancreatitis

 Syn. AIP , Autoimmune Pancreatitis

Signs & Symptoms

 Pancreatic enlargement
Ref: Uptodate [ Autoimmune pancreatitis]
Pancreatic mass
Note: mimicking carcinoma
Ref: Uptodate [ Autoimmune pancreatitis] Harrison [ 2446] Cecil [ 427]
Other organ involvement #Criteria
Ref: Harrison [ 2446]
History of chronic pancreatitis
Ref: Uptodate [ Autoimmune pancreatitis]

Physical Examination

 Pancreatic enlargement
Ref: Uptodate [ Autoimmune pancreatitis]
Pancreatic mass
Note: mimicking carcinoma
Ref: Uptodate [ Autoimmune pancreatitis] Harrison [ 2446] Cecil [ 427]
Weight loss
Ref: Harrison [ 2446]

Lab / Serology

 Elevated Anti-plasminogen-binding protein(PBP)
Ref: Uptodate [ Autoimmune pancreatitis]
Elevated serum IgG4 #Criteria
Note: more than two times the upper limit
Ref: Uptodate [ Autoimmune pancreatitis] Uptodate [ Clinical manifestations and diagnosis of primary sclerosing cholangitis] Harrison [ 2446]
Elevated lactoferrin
Ref: Uptodate [ Autoimmune pancreatitis]

Imagin Study

 Retroperitoneal fibrosis
Ref: Uptodate [ Autoimmune pancreatitis] Harrison [ 2446]
Diffuse swelling of pancreas
Ref: Harrison [ 2446]
ERCP reveal Diffuse irregular narrowing of pancreatic duct #Criteria
Ref: Harrison [ 2446]

Complication

 Peripancreatic vascular complications
Ref: Uptodate [ Autoimmune pancreatitis]

Risk Factors

 Male
Ref: Unknown [ 0]
Primary sclerosing cholangitis
Ref: Unknown [ 0]

Cause

Other