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Kawasaki Disease

 Syn. KD , Mucocutaneous lymph node syndrome , MLNS

Signs & Symptoms

 Anterior uveitis
Ref: Uptodate [ Kawasaki disease: Clinical features and diagnosis] Cecil [ 796]
Fever
Note: More than 5 days, Nonresponsive to antupyretic treatment
Ref: Uptodate [ Kawasaki disease: Clinical features and diagnosis] Harrison [ 2588] Cecil [ 796]
Fever More than 5 days
Note: More than 5 days, Nonresponsive to antupyretic treatment
Ref: Uptodate [ Kawasaki disease: Clinical features and diagnosis] Harrison [ 2588] Cecil [ 796]
High-grade fever
Note: More than 5 days, Nonresponsive to antupyretic treatment
Ref: Uptodate [ Kawasaki disease: Clinical features and diagnosis] Harrison [ 2588] Cecil [ 796]

Physical Examination

 Cutaneous desquamation
Ref: Uptodate [ Kawasaki disease: Clinical features and diagnosis]
Periungual desquamation
Ref: Uptodate [ Kawasaki disease: Clinical features and diagnosis]
Cracked lips
Ref: Uptodate [ Kawasaki disease: Clinical features and diagnosis]

Lab / Serology

 Elevated CRP
Ref: Uptodate [ Kawasaki disease: Clinical features and diagnosis]
Elevated ESR
Ref: Uptodate [ Kawasaki disease: Clinical features and diagnosis]
Thrombocytosis
Note: After day 7
Ref: Uptodate [ Kawasaki disease: Clinical features and diagnosis]

Imagin Study

 Splenomegaly
Ref: Uptodate [ Kawasaki disease: Clinical features and diagnosis]

Complication

 Brachial artery fusiform aneurysms
Ref: Uptodate [ Kawasaki disease: Clinical features and diagnosis]
Aseptic meningitis
Ref: Cecil [ 796]
Coronary artery aneurysms
Ref: Harrison [ 2588] Cecil [ 796]

Risk Factors

 Age < 20
Ref: Uptodate [ Kawasaki disease: Epidemiology and etiology]
Male
Ref: Uptodate [ Kawasaki disease: Epidemiology and etiology]

Cause

Other