Supporting Hours : Monday to Saturday - 8am to 10pm
New Visit

Hypercalcemia

 Syn. Raised serum calcium level , Increased calcium in blood , Blood calcium increased

Signs & Symptoms

 Familial hypocalciuric hypercalcemia
Ref: Harrison [ 313] Cecil [ 743]
Bowel hypomotility
Ref: Uptodate [ Clinical manifestations of hypercalcemia]
Vomiting
Ref: Uptodate [ Clinical manifestations of hypercalcemia]
Thiazides
Ref: Harrison [ 313] Cecil [ 741,743]

Physical Examination

 Neuropsychiatric disturbances
Note: due to hyperparathyroidism
Ref: Uptodate [ Clinical manifestations of hypercalcemia]
Confusion #Severe
Note: more likely to occur in older adults
Ref: Uptodate [ Clinical manifestations of hypercalcemia] Cecil [ 741]
Lethargy #Severe
Note: more likely to occur in older adults
Ref: Uptodate [ Clinical manifestations of hypercalcemia] Harrison [ 313]

Lab / Serology

 Elevated calcium
Note: MILD:12 to 14 mg/dL (3 to 3.5 mmol/L), Severe: calcium >14 mg/dL [3.5 mmol/L]
Ref: Uptodate [ Clinical manifestations of hypercalcemia]
Increased PTHrP level
Note: due to Underlying malignancy
Ref: Harrison [ 313]
Reversible fall in glomerular filtration rate
Note: In the serum calcium concentration (serum calcium values of 12 to 15 mg/dL [3 to 3.75 mmol/L]), due to Direct renal vasoconstriction, due to natriuresis, due to induced volume contraction
Ref: Uptodate [ Clinical manifestations of hypercalcemia] Cecil [ 741]

Imagin Study

 Deposition of calcium in coronary arteries
Ref: Uptodate [ Clinical manifestations of hypercalcemia]
Deposition of calcium in heart valves
Ref: Uptodate [ Clinical manifestations of hypercalcemia]
AV block
Ref: Harrison [ 313]

Complication

 Increased Serum 1 25(OH)2D levels
Note: due to granulomatous disorders
Ref: Harrison [ 313]
Cardiomyopathy
Ref: Uptodate [ Clinical manifestations of hypercalcemia]
Chronic renal insufficiency
Ref: Uptodate [ Clinical manifestations of hypercalcemia] Harrison [ 313] Cecil [ 741]

Risk Factors

Cause

 Renal carcinoma
Ref: Uptodate [ Clinical manifestations of hypercalcemia]
Squamous carcinoma
Ref: Uptodate [ Clinical manifestations of hypercalcemia]
Ovarian carcinoma
Ref: Uptodate [ Clinical manifestations of hypercalcemia]

Other