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Adrenal Crisis

 Syn. Addisonian crisis , Acute adrenal insufficiency , Acute adrenal failure

Signs & Symptoms

 Abdominal pain
Note: due to bilateral adrenal hemorrhage
Ref: Uptodate [ Clinical manifestations of adrenal insufficiency in adults] Harrison [ 2735] Cecil [ 643]
Back pain
Note: due to bilateral adrenal hemorrhage
Ref: Uptodate [ Clinical manifestations of adrenal insufficiency in adults]
Flank pain
Note: due to bilateral adrenal hemorrhage
Ref: Uptodate [ Clinical manifestations of adrenal insufficiency in adults]
Lower chest pain
Note: due to bilateral adrenal hemorrhage
Ref: Uptodate [ Clinical manifestations of adrenal insufficiency in adults]

Physical Examination

 Shock
Note: due to bilateral adrenal hemorrhage
Ref: Uptodate [ Clinical manifestations of adrenal insufficiency in adults] Harrison [ 2735]
Hypotension
Note: due to bilateral adrenal hemorrhage
Ref: Uptodate [ Clinical manifestations of adrenal insufficiency in adults] Harrison [ 2735]
Weight loss
Ref: Uptodate [ Clinical manifestations of adrenal insufficiency in adults] Harrison [ 2735] Cecil [ 643]

Lab / Serology

 Sudden fall in hemoglobin
Note: due to bilateral adrenal occult hemorrhage
Ref: Uptodate [ Clinical manifestations of adrenal insufficiency in adults]
Progressive hyperkalemia
Note: due to bilateral adrenal occult hemorrhage
Ref: Uptodate [ Clinical manifestations of adrenal insufficiency in adults]
Electrolyte abnormalities
Ref: Uptodate [ Clinical manifestations of adrenal insufficiency in adults] Harrison [ 2735]

Imagin Study

Complication

 Coma
Note: Decreased responsiveness.
Ref: Uptodate [ Clinical manifestations of adrenal insufficiency in adults] Harrison [ 2735]

Risk Factors

Cause

 21-hydroxylase deficiency Gr. Neonates
Ref: Uptodate [ Causes and clinical manifestations of primary adrenal insufficiency in children]
Congenital adrenal hyperplasia Gr. Neonates
Note: due to CYP21A2 deficiency, due to 21-hydroxylase deficiency
Ref: Uptodate [ Causes and clinical manifestations of primary adrenal insufficiency in children]
Bilateral adrenal injury
Note: due to blunt trauma complication
Ref: Uptodate [ Clinical manifestations of adrenal insufficiency in adults]

Other