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Hyperthyroidism

 Syn. Overactive thyroid , Thyrotoxicosis

Signs & Symptoms

 Muscle weakness
Ref: Uptodate [ Diagnosis of hyperthyroidism] Harrison [ 2704] Cecil [ 635]
Hyperphagia
Ref: Uptodate [ Overview of the clinical manifestations of hyperthyroidism in adults]
Skin lesion over anterior aspects of lower leg
Ref: Harrison [ 2704]
Skin lesion over lateral aspects of lower leg
Ref: Harrison [ 2704]

Physical Examination

 Proximal muscle weakness
Ref: Uptodate [ Diagnosis of hyperthyroidism] Harrison [ 2704] Cecil [ 635]
Indurated plaque
Ref: Harrison [ 2704]
Tremor
Ref: Uptodate [ Neurologic manifestations of hyperthyroidism and Graves' disease] Harrison [ 2704] Cecil [ 635]

Lab / Serology

 High T4
Ref: Uptodate [ Diagnosis of hyperthyroidism]
Low TSH
Ref: Uptodate [ Diagnosis of hyperthyroidism]
Decreased spermatogenesis Gr. Male
Ref: Uptodate [ Overview of the clinical manifestations of hyperthyroidism in adults]

Imagin Study

 ECG myocardial ischemia
Ref: Uptodate [ Cardiovascular effects of hyperthyroidism]
Increase in left ventricular mass index
Ref: Uptodate [ Cardiovascular effects of hyperthyroidism]
Increased ventricular irritability
Ref: Uptodate [ Cardiovascular effects of hyperthyroidism]

Complication

 Decreased spermatogenesis Gr. Male
Ref: Uptodate [ Overview of the clinical manifestations of hyperthyroidism in adults]
Sore throat
Note: due to Subacute thyroiditis
Ref: Harrison [ 2708]
Abnormal spermatogenesis Gr. Male
Ref: Uptodate [ Overview of the clinical manifestations of hyperthyroidism in adults]

Risk Factors

 Female
Ref: Uptodate [ Overview of the clinical manifestations of hyperthyroidism in adults]
Smoking
Ref: Uptodate [ Overview of the clinical manifestations of hyperthyroidism in adults]
Alemtuzumab intake
Ref: Uptodate [ Disorders that cause hyperthyroidism]

Cause

 Graves disease
Ref: Uptodate [ Disorders that cause hyperthyroidism]
Struma ovarii
Ref: Uptodate [ Disorders that cause hyperthyroidism]
Factitious ingestion of thyroid hormone
Ref: Uptodate [ Disorders that cause hyperthyroidism]

Other