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Intrahepatic Cholestasis

 Syn. Intrahepatic Biliary Stases , cholestasis intrahepatic , Bile Duct Obstruction, Intrahepatic

Signs & Symptoms

 Pruritus
Ref: Cecil [ 448-451]

Physical Examination

Lab / Serology

 Associated with hypercholesterolemia
Ref: Harrison [ 2897]
Moderate elevated liver aminotransferases
Ref: Harrison [ 2341]
Hyperlipoproteinemias
Ref: Harrison [ 2897]

Imagin Study

 Ultrasound demonstrate absence of biliary dilatation
Ref: Uptodate [ Approach to the patient with abnormal liver biochemical and function tests] Harrison [ 280]

Complication

Risk Factors

Cause

 Caused by defective excretion of bilirubin from hepatocytes into bile
Ref: Cecil [ 446]
Caused by hepatitis C
Ref: Uptodate [ Approach to the patient with abnormal liver biochemical and function tests]
Caused by hepatitis B
Ref: Uptodate [ Approach to the patient with abnormal liver biochemical and function tests]

Other