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Amebic Liver Abscess

 Syn. ALA , Abscess, Hepatic, Amebic , Hepatic amoebiasis

Signs & Symptoms

 Abdominal pain
Ref: Cecil [ 897]
Severe pain
Ref: Harrison [ 2333]
Right upper quadrant tenderness
Ref: Uptodate [ Extraintestinal Entamoeba histolytica amebiasis] Harrison [ 1571] Cecil [ 897]
Last less than 14 days
Ref: Harrison [ 1571] Cecil [ 897]

Physical Examination

 Fever
Note: 38.5 to 39.5ºC
Ref: Harrison [ 1571] Cecil [ 897]
Right upper quadrant tenderness
Ref: Uptodate [ Extraintestinal Entamoeba histolytica amebiasis] Harrison [ 1571] Cecil [ 897]
Acute onset
Ref: Epocrates [ https://online.epocrates.com/diseases/64031/Liver-abscess/Diagnostic-Approach]

Lab / Serology

 Positive antiamebic antibodies
Ref: Uptodate [ Extraintestinal Entamoeba histolytica amebiasis]
Leukocytosis
Note: >10,000 cells/μL
Ref: Uptodate [ Extraintestinal Entamoeba histolytica amebiasis] Harrison [ 1572] Cecil [ 897]
Abnormal alkaline phosphatase
Ref: Epocrates [ https://online.epocrates.com/diseases/64031/Liver-abscess/Diagnostic-Approach]

Imagin Study

 Right lobe involvement
Ref: Uptodate [ Extraintestinal Entamoeba histolytica amebiasis]
Solitary subcapsular lesions
Ref: Uptodate [ Extraintestinal Entamoeba histolytica amebiasis]
CT shows fluid collection with surrounding edema
Note: Tumors(solid radiographic appearance, calcification), Necrosis and tumor bleeding(fluid-filled appearance), Cysts(fluid collections without surrounding stranding or hyperemia)
Ref: Uptodate [ Pyogenic liver abscess]

Complication

 Dilutional hyponatremia
Ref: Cecil [ 458]
Flank dullness
Ref: Uptodate [ Evaluation of adults with ascites]
Excessive fatigue
Ref: Harrison [ 2412]

Risk Factors

 Male
Ref: Unknown [ 0]
Malignancy
Ref: Epocrates [ https://online.epocrates.com/diseases/64032/Liver-abscess/Risk-Factors]
Age > 50
Ref: Epocrates [ https://online.epocrates.com/diseases/64032/Liver-abscess/Risk-Factors]

Cause

 Caused by Entamoeba histolytica
Ref: Cecil [ 896]
Caused by E. histolytica
Ref: Harrison [ 1571]

Other